Funded Clinical Studies Dr. Epstein (Principle investigator): 

Clinical trials currently accruing:

1. Osteonecrosis of the Jaw (ONJ) Case Registry.  Amgen Protocol 20101102; Amgen, Inc.  PI: Joel Epstein

  • Clinical study of the natural history of osteonecrosis of the jaw in people treated with current bone sparing agent in cancer care (recruitment closed).

2. Gene expression analysis of brush cytology samples for oral Cancer screening; A nonivasive gene expression based

  • classifier for oral cancer. Arphion Ltd. R21-CA 139137.   
  • Brush cytology samples of oral lesions to evaluate gene expression that may assist in diagnosis of oral cancer. 

3. Procurement of human biospecimen for medical research: Oral rinse collection to assess molecular markers for oral and oropharyngeal cancer. Adept Protocol 03901. Adept Biopharmaceuticals LLC.

  • Oral rinse sample collected for biopsy proven oral and oropharyngeal cancer to assess molecular markers for cancer.

 4. Self-reported Oral Symptom Relief after use of Moistagen in a Dry Mouth Population.  Synedgen Inc. WIRB Protocol #20151479.

  • Patient reported outcomes of a trial of a novel dry mouth treatment product (recruitment closed).

5. Oral symptoms, dental care and oral function as self-reported  by people following head and neck cancer therapy.  Medactive Protocol 201401. WIRB Protocol #20142357, PI: Joel Epstein 


About Dr. Epstein

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Current Clinical Research